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Pragmatic trials are studies designed to inform the practice of clinical trials in real life. They are usually focused on the practical aspects of study design, including the recruitment process and consent in adherence, as well as the use of routinely available equipment.

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Another example of a pragmatic trial is the Home Blood Pressure Management (HBPM) study, which employed a variety of investigators and had participants from different geographical regions. This kind of heterogeneity, which is essential for 라이브 카지노 pragmatic trials to be valid and reduce bias in results, is also necessary. However, too much heterogeneity can lead to problems with the design of the trial.

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The purpose of pragmatic trials is to mimic real-life scenarios and to achieve the highest level of validity externally. Usually, they are ordered by policymakers and practitioners to help guide their decisions. They can also be used to determine the causality of an intervention and its results. They should not, however, be used to replace explanatory studies.

The pragmatism idea is controversial and there are concerns about whether pragmatic trials can replace explanatory tests or if they are an addition to them. Schwartz and Lellouch1 suggested the distinction between explanation trials, which validate a physiological or clinical hypothesis and pragmatic trials that inform the policy and practice of. They also suggested a framework dubbed PRECIS for pragmatic trials.2 This tool attempted to define the elements of a pragmatic study that includes recruitment, design, delivery of the intervention and its follow-up.

There is a growing increase in the number of pragmatic trials published. A recent Medline search using the terms pragmatic and naturalistic, restricted to controlled trials randomized to control (RCTs) produced 34 articles, which are shown in red in Figure 2. This suggests that the health sciences community is becoming more aware of the importance of pragmatism. However, it is important to keep in mind that the majority of these studies were conducted in primary care settings.